Acute Pancreatitis Randomized Controlled Studies
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Johnson CD, Kingsnorth AN, Imrie CW, McMahon MJ, Neoptolemos JP, McKay C, Toh SK, Skaife P, Leeder PC, Wilson P, Larvin M, Curtis LD: Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis. Gut 2001;48:62–69. Kalfarentzos F, Kehagias J, Mead N, Kokkinis K, Gogos CA: Enteral nutrition is superior to parenteral nutrition in severe acute pancreatitis: Results of a randomised prospective trial. Br J Surg 1997;84:1665–1669. Kingsnorth AN, Galloway SW, Formela LJ: Randomized, double-blind phase II trial of lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis. Br J Surg 1995;82:1414–1420. Luiten EJ, Hop WC, Endtz HP, Bruining HA: Prognostic importance of gram-negative intestinal colonization preceding pancreatic infection in severe acute pancreatitis. Results of a controlled clinical trial of selective decontamination. 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McKay CJ, Curran F, Sharples C, Baxter JN, Imrie CW: Prospective placebo-controlled randomised trial of lexipafant in predicted severe acute pancreatitis. Br J Surg 1997; 84:1239–1243. Mehal WZ, Culshaw KD, Tillotson GS, Chapman RW: Antibiotic prophylaxis for ERCP: A randomized clinical trial comparing ciprofloxacin and cefuroxime in 200 patients at high risk of cholangitis. Eur J Gastroenterol Hepatol 1995;7:841–845. Olah A, Belagyi T, Issekutz A, Gamal ME, Bengmark S: Randomized clinical trial of specific lactobacillus and fibre supplement to early enteral nutrition in patients with acute pancreatitis. Br J Surg 2002;89:1103–1107 Olah A, Pardavi G, Belagyi T, Nagy A, Issekutz A, Mohamed GE: Early nasojejunal feeding in acute pancreatitis is associated with a lower complication rate. Nutrition 2002;18: 259–262. 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Pancreatitis remains the most common and potentially fatal complication following ERCP. Various pharmacological agents have been used in an attempt to prevent post-ERCP pancreatitis, but most randomized controlled trials have failed to demonstrate their efficacy. Antiproteases, which have been clinically used to manage acute pancreatitis, would theoretically reduce pancreatic injury after ERCP ...
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تاریخ انتشار 2004